EGF Receptor Substrate 2 [DADE-pY-LIPQQG], Biotinylated – 1 mg

Overview

The EGF Receptor Substrate 2 [DADE-pY-LIPQQG], Biotinylated is a highly specific peptide designed for your scientific research needs. This phosphopeptide serves as an excellent substrate for mammalian protein tyrosine phosphatase 1B (PTP1B) and Yersinia PTP, making it a valuable tool in studying cellular signaling pathways. Its sequence comes from an autophosphorylation site (Tyr992) of the Epidermal Growth Factor Receptor (EGFR) and is uniquely labeled for fluorescence detection. The fluorescence increases significantly when the phosphate group is removed, allowing for precise assays.

Key Features

• Biotinylated EGF receptor substrate for targeted assays
• Excellent substrate for protein tyrosine phosphatase 1B and Yersinia PTP
• Derived from the autophosphorylation site of EGFR
• High sensitivity with fluorescence detection (Em = 305 nm, Ex = 282 nm)
• Available in a convenient 1 mg packaging

Specifications

FAQ

What applications can I use EGF Receptor Substrate 2 for?

This biotinylated peptide is ideal for assays related to protein tyrosine phosphatase activity, particularly in the study of signaling pathways involving the EGFR.

How is fluorescence detected with this substrate?

Fluorescence is detected based on the marked increase in signal when the phosphate group is removed from the peptide, allowing for sensitive measurement of PTP activity.

Can I find other peptides similar to this one?

Yes, you can explore our full range of peptidesincluding options like the PKG Substrate [RKRSRAE] and Autocamtide-2 [KKALRRQETVDAL], which may suit your research needs.

Enhance your research capabilities with the EGF Receptor Substrate 2 [DADE-pY-LIPQQG], Biotinylated. With its precise fluorescence detection and specialized substrate properties, it’s an excellent addition to your biological assays.

Related Products

• PKG Substrate [RKRSRAE], Glasstide
• Autocamtide-2 [KKALRRQETVDAL]
• CREBtide [KRREILSRRPSYR], 5-FAM labeled