Overview
PUMA BH3 is a peptide derived from the p53 upregulated modulator of apoptosis, designed to facilitate research on apoptosis mechanisms and p53 functionality. This peptide is instrumental in studying the intricate processes that regulate cell death and survival. In cellular biology, PUMA interacts with Bcl-2 proteins, localizing within mitochondria to trigger cytochrome C release, ultimately leading to apoptosis. Understanding these pathways can significantly impact cancer research, neuropathology, and therapeutic development.
Key Features
- High Purity: PUMA BH3 is synthesized to ensure maximum purity, enhancing experimental reliability.
- Research Applications: Ideal for apoptosis studies, cancer research, and biochemical assays.
- Biological Relevance: PUMA serves as a direct mediator of p53-induced apoptosis.
- Versatile Usage: Can be used in various assays, including protein-protein interactions and cellular assays.
- Custom Modifications: Explore options for modified peptides tailored to specific research needs.
Specifications
| Product Name | PUMA BH3 |
| Category | Peptides |
| Purity | ≥ 95% |
| Weight | 1 mg |
FAQ
What are the primary applications of PUMA BH3?
PUMA BH3 is primarily used in research focused on apoptosis, specifically to study the interactions between p53 and Bcl-2 family proteins. Researchers can employ this peptide in various experimental setups, including drug testing and cellular response evaluations.
How should PUMA BH3 be stored?
It is recommended to store PUMA BH3 in a cool, dry place, away from direct sunlight. For long-term storage, keep it in a -20°C freezer to maintain its stability and effectiveness.
Can PUMA BH3 be used in combination with other peptides?
Yes, PUMA BH3 can be effectively used in conjunction with other peptides, such as Autocamtide-2 or CREBtideto study complex signaling pathways and enhance your research outcomes.
If you’re looking to delve deeper into apoptosis research or peptide applications, consider exploring more in our peptides section. PUMA BH3 is now available for purchase, making it easy for you to get the peptides you need for your groundbreaking research.




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