Overview
Protegrin-1 (PG-1), amide, is an 18-amino-acid beta-hairpin antimicrobial peptide derived from porcine leukocytes. As a member of the cathelicidin family, PG-1 exhibits remarkable antimicrobial properties, making it an ideal choice for various applications in research and diagnostics. This peptide’s unique structure includes a modified C-terminal amide, enhancing its stability and functionality. Renowned for its broad-spectrum activity, PG-1 remains effective even in the presence of extracellular NaCl, allowing it to combat a wide array of bacterial strains, Candida albicans, and enveloped viruses.
In the fight against microbial resistance, Protegrin-1 stands out due to its dual disulfide bonds, which stabilize its beta-sheet structure and contribute to its potent antibacterial function. This means you can rely on PG-1 for effective pathogen management in your laboratory assays or therapeutic research. To explore more peptides that complement your work, check out our extensive collection of peptides.
Key Features
- 18-amino-acid beta-hairpin structure for enhanced stability
- Modified C-terminal amide improves functionality
- Broad-spectrum antimicrobial activity
- Active against various bacterial strains and fungi
- Effective in the presence of sodium chloride
- Ideal for research in antimicrobial resistance
Specifications
| Characteristic | Details |
|---|---|
| Product Name | Protegrin-1 (PG-1), amide |
| Composition | 18 amino acids |
| Origin | Porcine leukocytes |
| Category | Peptides |
FAQ
What are the main applications of Protegrin-1?
Protegrin-1 is primarily used in antimicrobial research, diagnostics, and therapeutic studies, particularly in investigating resistance to microbial infections.
How is Protegrin-1 affected by salt concentration?
PG-1 maintains its antimicrobial effectiveness even when sodium chloride concentrations are high, making it versatile for various experimental conditions.
Can I find other related peptides at AnaSpec?
Yes, AnaSpec offers a wide range of peptides. For example, consider exploring Autocamtide-2 or our CREBtide products for more research options.




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