[Lys(Me2)36]-Histone H3 (21-44)-GK(Biotin)

Overview

The [Lys(Me2)36]-Histone H3 (21-44)-GK(Biotin) peptide plays a crucial role in epigenetic regulation. This specifically designed lysine 36 dimethylated peptide is integral for recruiting the histone deacetylase complex to nucleosomes, effectively repressing transcription. Understanding its functionality allows researchers to explore the fascinating world of gene regulation in greater detail. This peptide’s unique modifications make it a valuable tool for studies related to cellular processes, including cell cycle proliferation.

Key Features

• Specifically designed for epigenetic research
• Demethylation by JMJD5 enhances transcription activation
• Facilitates the recruitment of histone deacetylase complex
• Available in a convenient format for easy handling
• Supports investigation of transcriptional repression mechanisms

Specifications

FAQ

What applications can this peptide be used for?

This peptide is ideal for studying epigenetic regulation, specifically in transcriptional repression and gene expression research. Its ability to recruit histone deacetylase complexes makes it essential for examining chromatin dynamics.

How should I store this peptide?

Store the [Lys(Me2)36]-Histone H3 peptide at -20°C for long-term storage. Avoid repeated freeze-thaw cycles to maintain peptide integrity.

Can this peptide be used in vivo?

While primarily designed for in vitro studies, consult product literature and published research for guidance on potential in vivo applications.

Explore our range of peptides for further research applications. For related enzyme studies, consider the innovative PKG Substrate or the versatile Autocamtide-2. Dive into transcription regulation with our CREBtide for a fluorescent approach.