[Arg(Me2a)3]-Histone H4 (1-23)-GGK(Biotin) – 1 mg

Overview

The [Arg(Me2a)3]-Histone H4 (1-23)-GGK(Biotin) peptide is a specialized research reagent designed for those studying epigenetic modifications. This peptide is unique due to its asymmetrical dimethylation at Arg3 and the addition of a biotinylated Lysine linked to a C-terminal GG linker. Such modifications are significant in regulating transcriptional activity, specifically influencing estrogen-regulated gene expression. As scientists delve deeper into the mechanisms of gene regulation, this peptide offers a valuable tool for experiments focused on histone modifications, acetylation processes, and transcriptional activation.

Key Features

• Asymmetrically dimethylated at Arg3, enhancing p300 acetylation.
• Biotinylated Lysine facilitates easy detection and purification.
• C-terminal GG linker improves solubility and stability.
• High purity (>95%) ensures reliable experimental results.
• Available in a convenient 1 mg format, ideal for various applications.

Specifications

FAQ

What is the significance of the biotinylation in this peptide?

The biotinylation allows for easier detection and purification of the peptide in various assays. It enables researchers to use streptavidin-based detection methods effectively.

How should I store this peptide once I receive it?

After reconstituting the peptide in distilled water, it’s recommended to store it at -20°C or -80°C to maintain stability and prevent degradation.

Can I use this peptide in in vivo studies?

This peptide is primarily designed for in vitro applications. If you’re looking for peptides suitable for in vivo studies, consider reviewing our range of labeled proteins and other [peptides](https://anaspecstore.com/product-category/our-catalog/peptides/) available.

For those in need of biotinylated substrates, check out our PKG Substrate or explore the Autocamtide-2 for related applications.

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