SensoLyte® Blue Glucocerebrosidase (GBA) Activity Assay Kit Fluorimetric – 1 kit
$642.00
Glucocerebrosidase/GBA (also called acid β-glucosidase, Glucosylceramidase) is a lysosomal enzyme responsible for the breakdown of glucocerebroside releasing glucose and ceramide.
Overview
The SensoLyte® Blue Glucocerebrosidase (GBA) Activity Assay Kit is designed for precise measurement of glucocerebrosidase activity in biological samples. This lysosomal enzyme plays a crucial role in breaking down glucocerebroside, leading to the release of glucose and ceramide. A deficiency in glucocerebrosidase, often due to genetic mutations, can result in the harmful accumulation of glucocerebroside, which is associated with Gaucher disease. Furthermore, mutations in the GBA1 gene have links to an increased risk for Parkinson’s disease and similar neurological disorders.
Key Features
- Fluorimetric detection allows for high sensitivity and specificity.
- Fast and easy protocol designed for optimal performance.
- Applicable to various sample types, including cell lysates and tissue extracts.
- Comes complete with all necessary reagents for quick setup.
- Supports research in lysosomal storage diseases and neurodegenerative disorders.
Specifications
| Catalog Number | AS-71084 |
| Format | Fluorimetric |
| Storage | -20°C |
FAQ
What type of samples can I analyze with this kit?
This assay kit is compatible with various sample types, including cell lysates, tissue extracts, and more. Ensure your samples are prepared according to the protocol for best results.
How sensitive is the assay?
The fluorimetric nature of the SensoLyte® Blue Glucocerebrosidase Activity Assay Kit provides high sensitivity, allowing you to detect even low levels of glucocerebrosidase activity.
Can this kit be used for research on Gaucher disease?
Yes, this assay kit is specifically designed for studying glucocerebrosidase activity, making it an excellent tool for research into Gaucher disease and related metabolic disorders.
With the SensoLyte® Blue Glucocerebrosidase Activity Assay Kit, you can effectively measure enzyme activity crucial for understanding lysosomal storage diseases. By incorporating this kit into your research, you support ongoing studies of neurological conditions linked to glucocerebrosidase deficiency. Browse our complete range of assay kits to find additional solutions for your laboratory needs.
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