SensoLyte® Green Glutaminyl Cyclase Activity Assay Kit Fluorimetric – 1 kit
$743.00
Many biologically active peptides and proteins have pyroglutamate (pGlu) as their first amino acid. This modification protects them from degradation by amino peptidases and in many cases determines functionality of protein or peptide.
Overview
The SensoLyte® Green Glutaminyl Cyclase Activity Assay Kit provides a crucial tool for studying biologically active peptides and proteins. Many of these molecules start with pyroglutamate (pGlu) as their first amino acid, a modification that not only protects them from degradation by amino peptidases but also influences their functionality. However, this modification comes with potential side effects. For example, pGlu-modified beta-amyloid peptides (pGlu-Aβ) are known for their propensity to aggregate rapidly. This aggregation can form toxic oligomers capable of damaging neurons, which is a key area of research in neurodegenerative diseases. If you’re exploring the roles of pGlu in protein functionality, this assay kit is an excellent choice.
Key Features
- Fluorimetric detection for accurate assessment of cyclase activity.
- Specifically detects glutaminyl cyclase with high sensitivity.
- Streamlined experimental protocol, saving you time.
- Comprehensive kit includes all necessary reagents.
- Suitable for various research applications in neurobiology and biochemistry.
Specifications
| Product Name | SensoLyte® Green Glutaminyl Cyclase Activity Assay Kit |
| Detection Method | Fluorimetric |
| Applications | Neurobiology, Protein Functionality Studies |
FAQ
What is the main use of the SensoLyte® Green Glutaminyl Cyclase Activity Assay Kit?
This assay kit is primarily used to measure the activity of glutaminyl cyclase, making it valuable for research into peptides and proteins modified by pyroglutamate, particularly those with implications in neurodegenerative diseases.
How does this assay kit work?
The assay utilizes fluorimetric detection, allowing for precise measurements of glutaminyl cyclase activity by measuring the fluorescence emitted during the reaction.
Can this kit be used for other peptide studies?
While the kit is specifically designed for glutaminyl cyclase activity, it can also provide insights for other peptides that undergo similar modifications, aiding in broader research applications.
For researchers studying the implications of pGlu-modifications in various conditions, this assay kit is an essential component of your toolkit. You might also find interest in our SensoLyte® Anti-Human MOG (1-125) Mouse IgG Specific ELISA Kit Colorimetric or the SensoLyte® Anti-PLP (178-191) IgG Quantitative ELISA Kit (mouse)both of which expand your research capabilities.
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