IRAK-4 Peptide Substrate; IRAK-1 (360-380) – 1 mg

Overview

The IRAK-4 Peptide Substrate; IRAK-1 (360-380) is a highly specific substrate peptide for Interleukin-1 Receptor-Associated Kinase 4 (IRAK-4). Derived from the IRAK-1 activation loop, this peptide comprises amino acids 360 to 380, focusing on the key Ser-376 residue. This residue is crucial as it acts as a primary phospho-acceptor for IRAK-1, allowing IRAK-4 to phosphorylate IRAK-1 in inflammatory signaling regulation. Understanding this interaction is essential for researchers studying inflammatory pathways and potential therapeutic targets.

Key Features

• Specific substrate for IRAK-4, targeting IRAK-1
• Derived from the IRAK-1 activation loop, amino acids 360-380
• Contains Ser-376, a critical phospho-acceptor residue
• Facilitates research in inflammatory signaling pathways
• Available in a 1 mg quantity

Specifications

FAQ

What is the purpose of the IRAK-4 peptide substrate?

The IRAK-4 peptide substrate serves to facilitate the study of IRAK-4’s role in the phosphorylation of IRAK-1, which is significant for understanding inflammatory signaling pathways.

How do I store the IRAK-4 peptide substrate?

To maintain stability and efficacy, store the peptide substrate at -20°C, avoiding repeated freeze-thaw cycles.

Is the IRAK-4 peptide substrate suitable for in vitro studies?

Yes, this peptide is designed for in vitro applications, making it ideal for research in signaling pathways related to inflammation and immune response.

Discover more about our PKG Substrate and check out additional options in our Peptides category. Whether you’re diving into inflammatory processes or exploring other signaling mechanisms, this IRAK-4 peptide substrate can enhance your research.

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