Overview
Exendin-4 (Exenatide) is a powerful peptide designed to mimic the action of glucagon-like peptide 1 (GLP-1), a key hormone in insulin regulation. By stimulating insulin release after meals, Exendin-4 plays a crucial role in managing blood sugar levels. Its structure, derived from the saliva of the Gila monster (Heloderma suspectum), provides a therapeutic approach that is both effective and long-lasting due to its extended half-life in plasma compared to GLP-1. This means it can consistently promote insulinotropic effects, making it a vital asset in diabetes research and treatment.
Key Features
- Effective GLP-1 receptor agonist for insulin release
- Longer half-life than natural GLP-1
- Supports blood sugar regulation
- Derived from Gila monster saliva
- Ideal for research and therapeutic applications
Specifications
| Property | Details |
|---|---|
| Name | Exendin-4 (Exenatide) |
| Category | Peptides |
| Molecular Weight | ~ 4200 Da |
| Sequence | 53% homologous to GLP-1 |
FAQ
What is Exendin-4 used for?
Exendin-4 is primarily used to stimulate insulin secretion in response to food intake, making it beneficial for diabetes management and research.
How does Exendin-4 compare to GLP-1?
While both target the GLP-1 receptor, Exendin-4 has a longer half-life and is more potent in inducing insulin release, which enhances its therapeutic potential.
Is Exendin-4 suitable for research applications?
Yes, Exendin-4 is widely used in research settings to study insulin signaling pathways and the physiology of diabetes.
Explore more about our peptides and consider adding PKG Substrate or Autocamtide-2 to complement your projects. Whether you’re studying hormonal responses or exploring insulin pathways, our vast selection of peptide products, including other peptidescan support your research needs.




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