Overview
Secretoneurin is a peptide consisting of amino acids 154 to 186 from secretogranin II, a neuropeptide that plays a significant role in various physiological processes. It is produced in the brain, adrenal medulla, and other endocrine tissues through the proteolytic processing of secretogranin II. This peptide is particularly important in the context of angiogenesis, where it functions as a direct angiogenic cytokine.
Key Features
- Stimulates endothelial cell proliferation.
- Inhibits apoptosis in endothelial cells.
- Activates crucial signaling pathways such as the mitogen-activated protein kinase (MAPK) system and the Akt pathway.
- Essential for research in neurobiology and vascular health.
- High purity and quality, suitable for various laboratory applications.
Specifications
| Property | Details |
|---|---|
| Name | Secretoneurin |
| Amount | 1 mg |
| Category | Peptides |
FAQ
What is the role of Secretoneurin in research?
Secretoneurin is essential for studying neurobiological processes and angiogenesis, making it valuable for researchers investigating vascular health and neuropeptide functions.
How does Secretoneurin affect endothelial cells?
This peptide prevents apoptosis in endothelial cells and promotes their proliferation, which is crucial for new blood vessel formation and overall vascular health.
Can I use Secretoneurin for in vitro studies?
Yes, Secretoneurin is designed for laboratory use and is perfect for in vitro studies focused on neurobiology and related fields. Consider pairing it with products like PKG Substrate or Autocamtide-2 for comprehensive research.
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