Integrin-Binding Site, GRGDNP – 1 mg

Overview

The Integrin-Binding Site, GRGDNP, is a carefully synthesized peptide available in a 1 mg unit. This RGD-containing sequence is essential for research into integrin interactions and cellular processes. Found within the extracellular matrix (ECM) in vital proteins like collagen, osteopontin, and fibronectin, this peptide plays a critical role in cell adhesion and signaling. Integrin-binding sites like GRGDNP facilitate the interaction between cells and their environment, making it invaluable for studies in cellular biology and tissue engineering.

Key Features

• Constitutes an RGD-containing sequence essential for integrin binding.
• Targets both alphavbeta3 and alpha5beta1 integrins.
• Significant in mediating cellular responses such as arteriolar vasoconstriction through endothelin interaction.
• Available in a convenient 1 mg format for diverse research applications.
• Produced with high purity to ensure reliable experimental outcomes.

Specifications

FAQ

What is the role of GRGDNP in biological research?

GRGDNP is commonly used to study integrin-mediated cell adhesion and migration. Its interaction with specific integrins enables researchers to understand cellular behaviors in various biological and pathological processes.

How should I store the Integrin-Binding Site, GRGDNP?

The peptide should be stored at -20°C to maintain its stability and potency. Ensure it is properly sealed to prevent moisture and degradation.

Can I use GRGDNP for in vivo studies?

While GRGDNP is primarily utilized in vitro for its integrin-binding properties, its relevance in vivo can depend on the experimental design and the specific biological context being studied.

For other peptides, consider exploring our extensive selection of peptides. If you’re looking for specific substrates, check out our PKG Substrate or the Autocamtide-2 options for your experiments. Ensure accurate results with peptides like CREBtidewhich are designed to enhance your research outcomes.