[Lys(Me3)4]-Histone H3 (1-25)-NH2 – 1 mg

Overview

The [Lys(Me3)4]-Histone H3 (1-25)-NH2 is an essential peptide for researchers focused on epigenetics and gene regulation. This synthetic peptide mimics the first 25 amino acids of human histone H3, providing a valuable tool for studying the trimethylation at lysine 4 (H3K4(Me3)). This post-translational modification is crucial as it indicates cellular states and lineage potential, differentiating gene expression patterns among expressed, poised, and repressed genes. Furthermore, H3K4(Me3) plays a significant role in marking imprinting control regions, making it indispensable in various biological studies.

Key Features

• Corresponds to amino acids 1-25 of human histone H3
• Trimethylated at lysine 4 for accurate modeling of gene regulation
• Essential for studying cellular state and lineage potential
• Helps differentiate genes that are actively expressed, poised for expression, or repressed
• Useful in research surrounding imprinting control regions

Specifications

FAQ

What is the significance of trimethylation at lysine 4?

Trimethylation at lysine 4 of histone H3 (H3K4(Me3)) is a critical marker for active gene transcription and plays a vital role in regulating gene expression, cellular differentiation, and lineage potential.

How can I use this peptide in my research?

This peptide can be utilized in various assays and experiments aimed at understanding gene regulation, epigenetic modifications, and cellular states. It is perfect for those studying histone modifications and their implications in gene expression.

Where can I find more related products?

You can explore our extensive range of peptides, including other histone variants and substrates, by visiting our peptides category. You might also be interested in our PKG Substrate or the Autocamtide-2 for further experimental applications.

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