Overview
Charybdotoxin (ChTX) is a potent Ca2+-activated K+ channel blocker, derived from the venom of the scorpion Leiurus quinquestriatus hebraeus. This unique peptide not only depolarizes peripheral T lymphocytes but also effectively inhibits their mitogen-induced proliferation. Its specific action makes it a valuable tool in research focusing on immune responses and cell proliferation. Researchers looking to understand the intricacies of T cell function will find ChTX to be an essential component in their studies.
Key Features
- Disulfide bridges at positions 7-28, 13-33, and 17-35 enhance stability.
- Useful in studying Ca2+-dependent K+ channels.
- Ideal for applications involving T lymphocyte activity and proliferation.
- High purity and reliability for accurate results.
- Comprehensive data supporting its functional applications in cell biology.
Specifications
| Product Name | Charybdotoxin |
| Weight | 0.1 mg |
| Source | Scorpion venom |
| Purity | ≥95% |
FAQ
What are the primary applications of Charybdotoxin?
Charybdotoxin is primarily used in research related to T lymphocyte function and cell proliferation studies. It serves as a potent blocker for specific K+ channels, helping to elucidate cellular mechanisms in immunology.
How should I store Charybdotoxin?
For optimal stability, store Charybdotoxin in a cool, dry place away from light. Follow the manufacturer’s guidelines for any specific storage recommendations.
Is Charybdotoxin suitable for in vivo studies?
While Charybdotoxin has shown promise in vitro, its application in in vivo studies should be approached with caution. It’s important to review relevant literature and guidelines to ensure proper use in live models.
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