Overview
Penetratin-Arg is a highly effective cell-penetrating peptide (CPP) derived from the third helix of the Drosophila Antennapedia homeodomain protein. Unlike its counterpart, Penetratin, which contains lysine residues, Penetratin-Arg replaces these with arginines, enhancing its ability to permeate cellular membranes. This peptide is structured as an alpha-helix in lipid environments, allowing it to enter cells at low micromolar concentrations without disrupting the membrane integrity.
As a versatile tool for research and therapeutic applications, Penetratin-Arg can be conjugated with larger molecules, making it a valuable vehicle for drug delivery. Whether you’re working in diagnostics or biopharmaceuticals, this peptide offers a reliable means of enhancing the efficacy of your targeted treatments. Check out our complete range of peptides for other innovative solutions.
Key Features
- Cell-penetrating peptide derived from Drosophila Antennapedia
- Enhanced membrane permeability thanks to arginine substitution
- Forms alpha-helix structure in lipid environments
- Low micromolar concentrations for efficient cell uptake
- Can be conjugated with large molecules for drug delivery applications
Specifications
| Product Name | Penetratin-Arg |
| Quantity | 1 mg |
| Type | Cell-penetrating peptide |
FAQ
What applications can Penetratin-Arg be used for?
Penetratin-Arg is useful in various applications, including drug delivery and cellular studies. Its ability to penetrate cell membranes makes it ideal for delivering larger therapeutic molecules.
Is Penetratin-Arg safe for use in vivo?
While Penetratin-Arg has been shown to penetrate cellular membranes effectively, safety in vivo can depend on the specific application and dosage. Always follow strict guidelines when using peptides in biological settings.
How does Penetratin-Arg compare to other CPPs?
Unlike some other cell-penetrating peptides, Penetratin-Arg offers enhanced cellular uptake due to its arginine residues. This feature can improve the delivery efficiency of therapeutic agents.
To purchase Penetratin-Arg or to explore other assay kits and reagents, visit our site. Discover how our advanced PKG Substrate and Autocamtide-2 products can complement your research needs.




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