Ser(OGlcNAc)]400-KWK-Tau (388-411)-KK(Biotin)-NH2 – 1 mg

Overview

The Ser(OGlcNAc)]400-KWK-Tau (388-411)-KK(Biotin)-NH2 is a specialized peptide that plays a critical role in neurological research, particularly concerning Alzheimer’s disease. This microtubule-associated protein Tau is crucial for maintaining neuronal structure and function. The hyperphosphorylation of Tau has been linked to Alzheimer’s, making it a significant focus for therapeutic and diagnostic research. The unique Ser-400 site on Tau is modified by O-GlcNAc, indicating its potential in understanding the pathogenesis of neurodegenerative diseases.

Key Features

• Highly purified peptide for optimal assay performance
• Biotinylated for easy detection and analysis
• Specifically designed for research on Tau protein modifications
• Ideal for studying mechanisms associated with Alzheimer’s disease
• 1 mg of peptide per vial for flexible experimentation

Specifications

FAQ

What is the significance of the O-GlcNAc modification in Tau?

The O-GlcNAc modification is crucial for understanding Tau’s role in Alzheimer’s disease, as it affects the protein’s phosphorylation status, influencing its aggregation and interactions.

How can this peptide be used in research?

This peptide can be utilized in various biochemical assays to study Tau protein interactions, modifications, and the molecular mechanisms underlying neurodegeneration.

Is the Ser(OGlcNAc)]400-KWK-Tau peptide suitable for in vivo studies?

While primarily designed for in vitro assays, it can provide insights for in vivo studies when incorporated into broader experimental frameworks.

To support your research, consider exploring our range of peptides and autocamtide-2. Enhance your studies with our high-quality PKG Substrate for optimal results.

Related Products

• CREBtide [KRREILSRRPSYR], 5-FAM labeled