Caspase 8 Substrate 1, chromogenic – 5 mg

Overview

Meet your research needs with our Caspase 8 Substrate 1a finely tuned chromogenic substrate specifically designed for granzyme B detection. This pNA-derived caspase substrate is ideal for those investigating caspase activities. When granzyme B cleaves the pNA peptide, it produces a chromogenic product that can be quantitatively measured at approximately 405 nm, which is reflective of its maximum absorption around 408 nm. This substrate allows for precise and efficient monitoring of caspase activity, which is crucial in apoptosis studies and various disease models.

Key Features

• Substrate for granzyme B, ensuring accurate assay results.
• Colorimetric detection of caspase activity via pNA cleavage.
• Optimized Km of 66 uM for dependable results.
• Monitored at ~405 nm for straightforward quantification.
• Available in a convenient 5 mg format, making it easy to incorporate into your experiments.

Specifications

FAQ

What is the primary use of Caspase 8 Substrate 1?

This substrate is primarily used for the colorimetric detection of caspase activities, particularly with granzyme B, making it essential for apoptosis research.

How do I store Caspase 8 Substrate 1?

Store the substrate at -20°C in a dry environment to maintain its stability and effectiveness for your assays.

Can I use this substrate in other assays?

While designed for granzyme B, Caspase 8 Substrate 1 may be applicable in other caspase assays, but it’s essential to validate its performance in your specific assays.

If you’re interested in expanding your assays, check out related products like our PKG Substrate or Autocamtide-2 for enhanced detection capabilities.

Order your Caspase 8 Substrate 1 today and take a step closer to precise detection in your research. This reliable substrate is readily available for purchase in our Peptides category.

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