TAT-NSF222 Fusion Peptide – 1 mg

Overview

The TAT-NSF222 Fusion Peptide is an innovative product designed for researchers focused on exploring the functionality of the N-ethylmaleimide-sensitive factor (NSF) within cellular processes associated with HIV. This fusion peptide is linked to an 11 amino acid cell-permeable human immunodeficiency virus (HIV) transactivating regulatory protein (TAT) domain through a Gly-Gly-Gly spacer, making it uniquely suited for studies involving cellular uptake and interaction of NSF-related pathways.

This peptide specifically encompasses the NSF domain, extending from amino acids 222 to 243, which is positioned right at the amino-terminal of the Walker A motif within the D1 domain of NSF. Its structure facilitates the inhibition of NSF ATPase activity, thus providing pivotal insights for scientists examining the mechanisms of HIV infection and potential therapeutic approaches. If you are engaged in assays related to ATPase activity, consider pairing this peptide with our PKG Substrate for comprehensive analysis.

Key Features

• Cell-permeable structure for effective delivery.
• Direct inhibition of NSF ATPase activity.
• Comprises essential NSF domain from amino acids 222 to 243.
• Versatile applications in HIV research and cellular studies.
• Compatible with a range of experimental protocols.

Specifications

FAQ

What is the primary application of the TAT-NSF222 Fusion Peptide?

This peptide is primarily used to study the function of NSF in cellular processes related to HIV by inhibiting its ATPase activity.

How should I store the TAT-NSF222 Fusion Peptide?

Store the lyophilized peptide at -20°C for long-term storage. Once reconstituted, it should be kept at 4°C and used within a few weeks.

Can I use this peptide in live cell experiments?

Yes, due to its cell-permeable nature, the TAT-NSF222 Fusion Peptide is suitable for live cell studies, enabling researchers to investigate cellular interactions and functionalities.

Explore more of our peptide offerings, including the Autocamtide-2 and CREBtide for enhanced research capabilities. Purchase the TAT-NSF222 Fusion Peptide today and take a step towards unraveling the complexities of NSF in HIV research.

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