Poly-gamma-D-Glutamic Acid Construct – 1 mg

Overview

The Poly-gamma-D-Glutamic Acid Construct, known as DPGA, is a specialized peptide crucial for research and diagnostic applications. This 1 mg construct relates directly to the Bacillus anthracis capsule, which is primarily composed of gamma DPGA. Understanding the role of gamma DPGA is essential, as it serves as a significant virulence factor for B. anthracis, contributing to the bacterial capability to evade the host’s innate defense mechanisms through its antiphagocytic properties.

This peptide is used by scientists and researchers who focus on infectious diseases, immunology, and vaccine development. Despite being a poor immunogen in its native form, when gamma DPGA is conjugated with a carrier protein, it can stimulate a robust immune response, leading to the production of serum antibodies. This property makes the Poly-gamma-D-Glutamic Acid Construct invaluable for developing effective diagnostic tests and therapeutic strategies.

Key Features

• 1 mg of Poly-gamma-D-Glutamic Acid Construct (DPGA)
• Relates to the Bacillus anthracis capsule
• Essential virulence factor of B. anthracis
• Inhibits innate host defense through antiphagocytic action
• Elucidates immune response when bound to carrier proteins

Specifications

Property	Details
Peptide Sequence	gamma-DPGA
Weight	1 mg
Category	Peptides

FAQ

What are the applications of Poly-gamma-D-Glutamic Acid Construct?

This peptide is primarily used in research related to Bacillus anthracis, infection mechanisms, and immune responses. It is essential for the development of assays and vaccines.

How does gamma DPGA function as a virulence factor?

Gamma DPGA acts as a protective capsule for Bacillus anthracis, inhibiting phagocytosis by immune cells, allowing the bacteria to evade the host’s immune response.

Can this peptide be used for antibody production?

Yes, although gamma DPGA is a poor immunogen by itself, when conjugated to a carrier protein, it can stimulate the production of specific antibodies, useful for diagnostic purposes.

If you’re looking to enhance your research on Bacillus anthracis or develop new assays, consider purchasing the Poly-gamma-D-Glutamic Acid Construct today. This peptide will provide the reliability and specificity you’ve been searching for in your experiments.

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