Crosstide [GRPRTSSFAEG] – 5 mg

Overview

Crosstide [GRPRTSSFAEG] is a specialized peptide analog of glycogen synthase kinase-3 (GSK-3). This peptide serves as a natural substrate for Akt/PKB, crucial in various signaling pathways in biological research. Its design ensures specificity toward the PKBα, PKBβ, and PKBγ isoforms, making it an essential component for studies related to kinase activity and signaling. Researchers interested in examining cell signaling can significantly enhance their experiments with Crosstide.

Key Features

• Functions as a substrate for Akt/PKB, vital for signaling studies.
• Similar specificity towards PKB isoforms: PKBα, PKBβ, and PKBγ.
• Recognized by MAPKAP kinase-1 and p70S6K.
• Can be obtained as fluorescent and biotinylated peptides, maintaining similar enzyme activities.
• Available in a convenient 5 mg format, ideal for various applications.

Specifications

FAQ

What applications can I use Crosstide for?

Crosstide is primarily used in studies related to cell signaling, particularly in studies involving enzyme assays and kinase activity. Its interaction with Akt/PKB pathways makes it suitable for research in cancer and metabolic diseases.

How does Crosstide compare to other peptides?

When compared with other peptides like PKG substrate [RKRSRAE] or Autocamtide-2 [KKALRRQETVDAL]Crosstide offers unique specificity towards the PKB isoforms, making it particularly valuable in research targeting these pathways.

Can I get Crosstide in different labeling formats?

Yes, Crosstide comes in various formats, including fluorescent and biotinylated versions, allowing researchers to choose based on their experimental needs. These formats can be beneficial in assays requiring detection and quantification.

Explore our full range of peptides for further research enhancements, including options like CREBtide [KRREILSRRPSYR], 5-FAM labeled.