Overview
Tau (Tau-441) is a vital human recombinant protein that plays a key role in the central nervous system (CNS). Found predominantly in the brain, Tau is a microtubule-associated protein that promotes the assembly and stabilization of neuronal microtubules. Its significance is underscored by the existence of multiple isoforms; Tau-441 is the longest, consisting of 441 amino acids and a molecular weight of 45.8 kDa.
Under normal physiological conditions, Tau undergoes various modifications including phosphorylation and truncation, which can impact its functionality. The ability to study these changes is crucial for understanding neurodegenerative diseases, particularly those associated with Tau pathology. By purchasing Tau-441, you’re equipped to explore the intricacies of Tau and its implications in neurological research.
Key Features
- Human recombinant Tau (Tau-441) protein, GST tagged for enhanced purification.
- Key role in promoting and stabilizing neuronal microtubules.
- Facilitates the study of Tau’s involvement in neurodegenerative diseases.
- Comes in a ready-to-use format for convenient experimental applications.
- Linked to ongoing research efforts in understanding CNS disorders.
Specifications
| Attribute | Details |
|---|---|
| Product Name | Tau (Tau-441), human recombinant, GST tagged |
| Isoform | Tau-441 |
| Amino Acids | 441 |
| Molecular Weight | 45.8 kDa |
| Source | Human recombinant |
FAQ
What is the role of Tau in the CNS?
Tau is primarily involved in stabilizing microtubules in neurons, aiding in their structure and function. Its disruptions are linked to various neurodegenerative diseases.
How is Tau-441 different from other isoforms?
Tau-441 is the longest isoform of Tau, which contains all functional domains necessary for its role in microtubule stabilization and assembly.
How can I use Tau-441 in my research?
Tau-441 can be utilized in studies focused on neurodegenerative diseases, specifically those involving Tau phosphorylation and its effects on neuronal health. You may also be interested in related products like Recombinant human MOG (1-125) for comprehensive analyses.
Order your Tau (Tau-441), human recombinant, GST tagged today and enhance your research into neuronal function and degeneration.
Related Products
Browse more in Catalog recombinant.




Reviews
There are no reviews yet.