Overview
The MMP-13 (Catalytic Domain), human recombinant is a vital enzyme in the family of matrix metalloproteinases (MMPs), renowned for their role in tissue remodeling and matrix degradation. This enzyme is secreted initially as a 60-kDa proenzyme and is activated upon cleavage to become the mature 48-kDa form. MMP-13 targets key components like collagen, gelatin, aggrecan, plasminogen, and CXCL12, making it essential for research in areas such as tissue repair, bone remodeling, and the menstrual cycle.
Key Features
- Recombinant human MMP-13 for reliable experimental results
- Active form available, allowing for direct application in studies
- Essential for research in connective tissue breakdown and repair
- Supports studies in physiological and pathological processes
- Available in a convenient 1 µg unit
Specifications
| Property | Details |
|---|---|
| Category | Catalog recombinant |
| Source | Human cell line |
| Form | Recombinant protein |
| Weight | 48 kDa (active) |
FAQ
What is MMP-13 used for in research?
MMP-13 is crucial in studies related to tissue remodeling, bone biology, and the repair of connective tissues. Its ability to break down various extracellular matrix components makes it a key player in understanding these biological processes.
How is MMP-13 activated?
The native MMP-13 is synthesized as an inactive 60-kDa proenzyme. It undergoes proteolytic cleavage to become the active 48-kDa enzyme, which is instrumental in various physiological functions.
Can I use MMP-13 in my assays?
Yes, the MMP-13 (Catalytic Domain), human recombinant is specifically designed for use in assays and experiments, providing a reliable tool for your research needs.
For comprehensive studies, consider exploring our other recombinant proteins, like recombinant human MOG or EndoClear™ Plus human recombinant a-Synuclein proteinwhich can complement your research on protein interactions and physiological indicators.
This MMP-13 (Catalytic Domain) is not just a product; it’s a crucial element in your scientific explorations. Order yours today and ensure your research is backed by high-quality reagents designed for superior performance.
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