Overview
The Human MMP-2, or 72-kDa gelatinase-A, is a crucial enzyme implicated in tumor development and metastasis. This recombinant protein is synthesized as a pro-enzyme and is essential for researchers aiming to explore cancer therapies. By purchasing our Human MMP-2, you gain access to a potent tool for your cancer research projects. With proven involvement in key cellular processes, MMP-2 is a valuable target for therapeutic intervention.
Key Features
- Produced as a pro-enzyme from its DNA sequence.
- Transfected into CHO cells for high-quality expression.
- Fully activated by incubation with 1 mM APMA.
- Supports investigations into tumor biology and metastasis.
- Available in a convenient 100 µL format.
Specifications
| Item | Details |
|---|---|
| Protein Type | Recombinant |
| Molecular Weight | 72 kDa |
| Volume | 100 µL |
FAQ
What is MMP-2, and why is it important?
MMP-2 is a member of the matrix metalloproteinase family, known for its role in breaking down extracellular matrix components. This function is pivotal in cancer progression and metastasis, making it a critical target for research.
How do I activate MMP-2?
To fully activate pro-MMP-2, incubate it with 1 mM APMA at 37°C for 20 minutes to an hour. This step is crucial for its enzymatic activity.
Can I use MMP-2 in other research areas?
While primarily connected to cancer research, MMP-2 can also be explored in studies related to tissue remodeling, wound healing, and other physiological processes.
Get your Human MMP-2 today and advance your research in cancer biology. Visit our catalog of recombinant proteins for more options that may complement your studies.




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