Human MMP-14 – 100 µL

Overview

Human MMP-14, also referred to as membrane-type MMP (MT1-MMP), is crucial in the process of tumor invasion. As a member of the matrix metalloproteinases (MMPs) family, MMP-14 is a zinc endopeptidase that can digest components of the extracellular matrix. This enzyme is particularly significant as it is expressed on the surface of invasive tumor cells and in stromal cells of various carcinomas, including human colon, breast, and head and neck cancers. Understanding the role of MMP-14 in tumor biology is essential for advancing cancer research and therapy.

Key Features

• Expressed on invasive tumor cell surfaces
• Involved in the degradation of extracellular matrix components
• Important for studies on tumor invasion and metastasis
• Available in a convenient 100 µL format
• Part of our comprehensive catalog of recombinant proteins

Specifications

FAQ

What is the role of MMP-14 in cancer?

MMP-14 plays a pivotal role in tumor invasion by degrading the extracellular matrix, allowing tumor cells to migrate and invade surrounding tissues.

How is Human MMP-14 prepared?

This protein is produced as a zymogen, which includes a prodomain, a catalytic domain, a hinge region, a hemopexin-like domain, and a transmembrane region, ensuring its proper activity in biological assays.

What types of experiments can I use MMP-14 for?

You can use Human MMP-14 in a variety of studies, including cancer research, drug development, and to understand tumor biology. It’s an essential component in assay kits designed for detecting and quantifying proteins related to tumor invasion.

To explore more about proteins that complement MMP-14 in research, consider checking out our Recombinant mouse MOG (1-125) or our Recombinant human MOG (1-125). For those focused on synuclein studies, our EndoClear™ Plus human recombinant a-Synuclein protein might also be beneficial.

Order your Human MMP-14 today and enhance your research with this critical enzyme.

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