40Gap 27, Connexin Mimetic – 1 mg

Overview

The 40Gap 27, Connexin Mimetic is a specialized peptide designed to mimic the GAP27 domain of the second extracellular loop of the vascular connexin Cx40. This peptide plays a crucial role in research focused on gap junction communication, specifically in understanding how oxidative stress affects endothelial functions.

When used in experimental settings, 40Gap27 has demonstrated the ability to attenuate endothelium-dependent subintimal smooth muscle hyperpolarization. This makes it a valuable tool for researchers studying vascular health and disease mechanisms.

Key Features

• Corresponds to GAP27 domain of Cx40
• Investigates gap junction communication
• Useful for studying oxidative stress effects
• Attenuates specific smooth muscle responses
• 1 mg per vial for varied experimental use

Specifications

FAQ

What is the primary use of 40Gap 27?

40Gap 27 is primarily used in research to investigate mechanisms of endothelial dysfunction, particularly under oxidative stress conditions that affect gap junction communication.

How should 40Gap 27 be stored?

This peptide should be stored at -20°C to maintain its stability and integrity over time. Always refer to the product’s specific storage recommendations.

Are there any common applications for this peptide?

Common applications include studying cardiovascular health, endothelial signaling pathways, and the effects of oxidative stress on vascular function, which are crucial for developing treatments for vascular diseases.

For more related products, check out our range of peptides and other assay kits tailored to enhance your research work.

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