Adeno-Associated Virus Epitope 2 (AAV2) – 1 mg

Overview

The Adeno-Associated Virus Epitope 2 (AAV2) is a specialized peptide designed for advanced research in virology and immunology. This peptide, derived from the capsid of adeno-associated virus 2, serves as a crucial CD8 T cell epitope. Understanding its role is vital, especially in studies related to liver toxicity observed during clinical trials where AAV2 was delivered systemically to patients with hemophilia. The immune response triggered by capsid-specific T cells led to the destruction of vector-transduced hepatocytes, highlighting the importance of this peptide in immunological research.

Key Features

• Derived from the capsid of adeno-associated virus 2
• Essential for studying immunodominant CD8 T cell epitopes
• Contributes to understanding liver toxicity in AAV2 clinical applications
• Ideal for researchers focusing on viral capsid interactions with the immune system
• Available in a convenient 1 mg format for easy use in experiments

Specifications

FAQ

What is the primary use of AAV2 peptide?

The AAV2 peptide is primarily used in research to explore the immunogenicity of adeno-associated viruses, particularly in understanding T cell responses related to liver toxicity.

How should I store the Adeno-Associated Virus Epitope 2?

Store the peptide at -20°C to maintain its stability and integrity over time. Always ensure that it is kept away from moisture and light.

Can AAV2 peptide be used in animal studies?

Yes, the AAV2 peptide is suitable for various studies, including animal research, to assess immune responses and potential vector-related side effects.

This peptide is a vital addition to your research arsenal, particularly if you’re investigating immunological responses or working with viral vectors. Adding the Adeno-Associated Virus Epitope 2 to your laboratory supplies may provide important insights into T cell interactions and safety concerns in gene therapy applications. If you’re interested in expanding your research capabilities, consider exploring our range of related products, including PKG Substrate for enzyme assays or Autocamtide-2 for studying protein modifications. Don’t miss the chance to enhance your projects with quality peptides from our catalog, including variations suitable for fluorescent labeling and other specialized applications.

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