[Arg(Me2a)3]-Histone H4(1-21)-GGK(Biotin) – 1 mg

Overview

Introducing [Arg(Me2a)3]-Histone H4(1-21)-GGK(Biotin), a specialized peptide designed for advanced research in epigenetics. This peptide encompasses the first 21 amino acids of histone H4 and is asymmetrically dimethylated at Arg3. The unique modification of adding both methyl groups to one nitrogen of the guanidinium group enhances its biological activity, making it a critical component for studies involving gene regulation and transcriptional activation.

Key Features

• Asymmetrically dimethylated at Arg3 for enhanced activity
• C-terminal GG linker for stability and functionality
• Biotinylated Lys allows for easy detection and labeling
• Provided at >95% peptide purity for reliable results
• Available in a convenient 1 mg format

Specifications

FAQ

What is the significance of methylation at Arg3 in histone H4?

Methylation at Arg3 of histone H4 is crucial for transcriptional activation, facilitating the acetylation of histone tails by enzymes like p300, thus playing a vital role in gene expression regulation.

How should I store this peptide?

It is recommended to store [Arg(Me2a)3]-Histone H4(1-21)-GGK(Biotin) at -20°C to maintain its integrity and effectiveness. Ensure the vial is tightly sealed to prevent moisture absorption.

Can this peptide be used in Western blotting?

Yes, the biotinylated component of this peptide enables easy detection in various applications, including Western blotting, making it a versatile choice for protein analysis.

Add [Arg(Me2a)3]-Histone H4(1-21)-GGK(Biotin) to your research toolkit now, and explore the world of histone modifications. Enhance your experiments with high-quality peptides and consider checking out other related products such as Autocamtide-2 or CREBtide. Shop today to elevate your research.

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