Overview
Cyclo (-RGDfK) is a potent cyclic hexapeptide specifically designed for binding to integrin alpha(IIb)beta(3) receptors. This peptide, featuring the essential Arg-Gly-Asp (RGD) sequence, plays a crucial role in various studies, notably in cancer research. When labeled with 125I, it has demonstrated a high affinity for αvβ3 receptors found in neovascular blood vessels associated with major human cancers. This specificity makes Cyclo (-RGDfK) an invaluable tool for researchers exploring integrin-targeted therapies and diagnostics.
Key Features
- Highly specific binding to integrin alpha(IIb)beta(3) receptors
- Contains the essential Arg-Gly-Asp (RGD) sequence
- Proven high-affinity interaction in cancer research
- Versatile applications in assay development and diagnostic research
- Available in a convenient 1 mg vial
Specifications
| Property | Details |
|---|---|
| Catalog Number | Cyclo (-RGDfK) |
| Quantity | 1 mg |
| Type | Peptide |
FAQ
What are the main applications of Cyclo (-RGDfK)?
Cyclo (-RGDfK) is primarily used in cancer research, particularly for studying neovascularization and integrin-targeted therapies. Its binding properties make it an excellent candidate for assay development.
How should Cyclo (-RGDfK) be stored?
For optimal stability, store Cyclo (-RGDfK) at -20°C in a dry environment. Avoid repeated freeze-thaw cycles to maintain peptide integrity.
Can I use this peptide for in vivo studies?
Yes, Cyclo (-RGDfK) has been utilized in various in vivo studies, primarily for its ability to bind specifically to αvβ3 receptors in cancerous tissues.
If you’re looking to enhance your research capabilities, consider adding Cyclo (-RGDfK) to your lab’s repertoire. For complementary products, explore our collection of peptides and labeling kits, ensuring you have the tools necessary for successful experimental outcomes.




Reviews
There are no reviews yet.