Exendin (5-39) – 1 mg

Overview

Exendin (5-39) is a crucial tool for researchers focused on studying the regulation of insulin secretion. This truncated version of the Exendin-4 peptide serves as a potent glucagon-like peptide 1 (GLP-1) receptor antagonist, offering unique insights into glucose metabolism and potential therapeutic applications.

Unlike its full-length counterpart, Exendin-4, which enhances GLP-1-stimulated insulin release, Exendin (5-39) actively inhibits this process after food intake. By antagonizing GLP-1 action, this peptide plays a significant role in understanding how insulin responses can be modulated, making it valuable in diabetes research and development.

Key Features

• Functions as a GLP-1 receptor antagonist
• Inhibits GLP-1-stimulated insulin secretion
• Important for research into metabolic diseases
• Available in a convenient 1 mg vial
• High purity for reliable experimental results

Specifications

FAQ

What research applications is Exendin (5-39) useful for?

This peptide is widely used in studies focused on diabetes, obesity, and metabolic syndrome. Its ability to antagonize GLP-1 receptors provides insights into insulin regulation and glucose homeostasis.

How should Exendin (5-39) be stored?

Store Exendin (5-39) at -20°C to maintain its stability and activity. Make sure to avoid repeated freeze-thaw cycles to preserve peptide integrity.

Can I use Exendin (5-39) in in vitro assays?

Yes, Exendin (5-39) is suitable for various in vitro assays aimed at studying GLP-1 receptor interactions and insulin secretion pathways. For enhanced results, consider using our PKG substrate or other peptide options available in our catalog.

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