[Lys(Ac)12]-Histone H4 (1-21)-GGK(Biotin) – 1 mg

Name: [Lys(Ac)12]-Histone H4 (1-21)-GGK(Biotin) | AnaSpec
SKU: AS-64849-1
Price: 364.00 USD
Availability: InStock

$364.00

[Lys(Ac)12]-Histone H4 (1-21)-GGK(Biotin), Acetylation causes structural changes: amplify binding transcription factors to recognition sites in nucleosome.

SKU: AS-64849-1 Category: Peptides Tags: biotin, histone, peptides

Description
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Overview

Discover the power of [Lys(Ac)12]-Histone H4 (1-21)-GGK(Biotin), a specialized peptide designed for precise biochemical research. This peptide is a segment of histone H4, acetylated at lysine 12, which plays a pivotal role in chromatin structure and gene regulation. Acetylation of this histone variant is crucial as it facilitates the binding of transcription factors to their specific recognition sites within nucleosomes, thus impacting gene expression significantly.

Key Features

Acetylated histone H4 (1-21) for enhanced protein interaction studies.
Includes a biotinylated lysine for easy detection and purification.
High purity level of >95% ensures reliable experimental results.
Conveniently provided in powder form, ensuring stability and ease of use.
Ideal for studies in gene regulation and chromatin dynamics.

Specifications

Attribute	Details
Product	[Lys(Ac)12]-Histone H4 (1-21)-GGK(Biotin)
Purity	>95%
Format	Lyophilized powder
Quantity	1 mg
Storage	Store at -20°C

FAQ

What is the significance of acetylation on histones?

Acetylation alters the structure of histones, which in turn can affect how tightly DNA is wound around them. This has implications in gene expression, as it can either promote or inhibit the access of transcription machinery to DNA.

How can I use this peptide in my research?

This peptide can be utilized in various assays to study transcription factor binding, chromatin remodeling, and other aspects of gene regulation. Its biotinylated form allows for easy detection using streptavidin-coated surfaces or other detection methods.

What other related products does AnaSpec offer?

AnaSpec provides a wide range of peptides and assay kits that can complement your research needs. Explore our peptides or consider our PKG Substrate for specific assays here.

Invest in [Lys(Ac)12]-Histone H4 (1-21)-GGK(Biotin) today and enhance your research capabilities. This peptide is not only an essential tool for understanding gene regulation but also a critical component in advancing your scientific inquiries.