[Lys(Ac)5/8/12/16]-Histone H4 (1-21)-GGK(Biotin) – 1 mg

Overview

Introducing the [Lys(Ac)5/8/12/16]-Histone H4 (1-21)-GGK(Biotin), a specialized peptide designed for research in gene expression and chromatin remodeling. This peptide, acetylated at lysine residues 5, 8, 12, and 16, plays a key role in enhancing DNA replication during mitosis. Its unique C-terminal GG linker, followed by biotinylated lysine, makes it ideal for various applications, including affinity purification and detection in your studies.

Key Features

• Acetylated at lysines 5, 8, 12, and 16, crucial for histone function.
• Biotinylated for easy attachment to streptavidin-based detection methods.
• High purity greater than 95%, ensuring reliable performance in experiments.
• Re-lyophilized to powdered form for convenient storage and handling.
• Ideal for studies involving chromatin dynamics and DNA replication.

Specifications

FAQ

What is the significance of histone acetylation?

Histone acetylation is essential for regulating gene expression. The acetyl groups add a negative charge to histones, reducing their affinity for DNA and promoting a more open chromatin structure that facilitates transcription.

How can I use this peptide in my experiments?

This peptide can be employed in a variety of assays, including pull-down assays, western blots, and ELISA systems. Its biotin tag enables easy detection and purification using streptavidin-binding methods.

Is this peptide suitable for in vivo studies?

While this peptide is primarily designed for in vitro experiments, its biochemical properties allow for potential applications in in vivo studies, depending on your research goals and methods.

For additional reliable research tools, explore our range of peptides or check out the Autocamtide-2 and CREBtide options available at AnaSpec. Get your [Lys(Ac)5/8/12/16]-Histone H4 (1-21)-GGK(Biotin) today to enhance your research endeavors.

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