SensoLyte® HAT (p300) Assay Kit Fluorimetric – 1 kit
$635.00
SensoLyte® HAT (p300) Assay Kit Fluorimetric for screening of enzyme inhibitors and for continuous assay of Histone acetyltransferase p300 activity.
Overview
The SensoLyte® HAT (p300) Assay Kit Fluorimetric is designed specifically for the screening of enzyme inhibitors and the continuous assessment of Histone Acetyltransferase p300 activity. This enzyme plays a crucial role in the regulation of gene expression by modifying histones and non-histone proteins through acetylation. The acetylation process significantly impacts transcriptional activation, DNA replication, DNA repair, and protein, protein interactions. Misregulation of HATs, particularly p300, has been linked to various human tumors, making this assay kit vital for understanding cancer mechanisms and potential therapeutic developments.
Key Features
- Efficiently screens for p300 enzyme inhibitors.
- Allows continuous monitoring of p300 activity.
- Utilizes a fluorimetric approach for high sensitivity and specificity.
- Ideal for research in cancer biology and epigenetics.
- Easy-to-follow protocol ensures reproducible results.
Specifications
| Component | Details |
|---|---|
| Kit Size | 1 Kit |
| Detection Method | Fluorometric |
| Target Enzyme | Histone Acetyltransferase p300 |
| Application | Screening and assay of enzyme activity |
FAQ
What is the purpose of the SensoLyte® HAT (p300) Assay Kit?
This assay kit is designed to screen for HAT enzyme inhibitors and evaluate the activity of the p300 enzyme, which is critical in gene regulation and associated with tumorigenesis.
How is the assay performed?
The kit provides a detailed protocol that guides you through the setup and execution of the assay, enabling efficient and accurate measurement of p300 activity.
Can this kit be used in combination with other assays?
Yes, the SensoLyte® HAT (p300) Assay Kit can be integrated with other assays, such as the SensoLyte® Anti-Human MOG (1-125) Mouse IgG Specific ELISA Kit and the SensoLyte® Anti-PLP (178-191) IgG Quantitative ELISA Kit, to broaden your research scope.
This kit not only helps in understanding the complexities of histone modification but also aids in drug discovery processes. Purchase the SensoLyte® HAT (p300) Assay Kit today and enhance your research in epigenetics and oncology.
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