Overview
hBD-1, or human beta-defensin 1, is a significant peptide in the realm of antimicrobial defense. With a molecular weight of 3.9 kDa and composed of 36 amino acids, this peptide plays a vital role in the immune response by targeting pathogenic microorganisms, including bacteria like E. coli. Its unique structure includes a beta sheet stabilized by three intramolecular disulfide bonds, ensuring its stability and effectiveness in various biological conditions. Produced by various epithelial tissues, particularly in the urogenital and respiratory tracts, hBD-1 is known to chemoattract CC-CCR6-expressing cells, thereby enhancing immune response where it’s needed most.
Key Features
- Exhibits antimicrobial activity against a broad range of microorganisms
- Targets specific cells to stimulate immune response
- Stable structure with disulfide bonds for enhanced effectiveness
- Produced in key tissues relevant to infection defense
- Available for purchase in a 0.1 mg vial
Specifications
| Product Name | hBD-1, b-Defensin-1, human |
| Weight | 0.1 mg |
| Sequence | 36-amino acids |
| Molecular Weight | 3.9 kDa |
FAQ
What is the role of hBD-1 in the immune system?
hBD-1 acts as a natural antimicrobial agent, protecting the body by neutralizing harmful pathogens such as bacteria and viruses.
How is hBD-1 produced in the body?
This peptide is naturally produced by epithelial cells found in various tissues, including the respiratory and urogenital areas, where it is crucial for first-line defense against infections.
Is hBD-1 safe for research use?
Yes, hBD-1 is extensively studied and used in various research applications due to its well-documented safety and efficacy profiles.
For anyone looking to incorporate powerful antimicrobial properties into their research, hBD-1 is a compelling option. You can find complementary products like PKG Substrate and Autocamtide-2 to enhance your experimental setup. Don’t miss the chance to purchase hBD-1 today and explore the full potential of this essential peptide in your work.
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