[Lys(Ac)56]-Histone H3 (44-63) – 1 mg

Overview

Discover the significance of [Lys(Ac)56]-Histone H3 (44-63), a peptide essential for understanding chromatin regulation and cellular processes. This peptide, specifically designed with acetylation at Lys56, plays a vital role during premeiotic and mitotic S phases, crucial periods in the cell cycle where DNA replication and repair occur. The acetylation process is facilitated by the Rtt109-Vps75 histone acetyltransferase complex, emphasizing its importance in maintaining chromatin structure and function.

The implications of Lys56 acetylation extend beyond normal cell division, as deficiencies in this modification can lead to spontaneous chromosome breaks during mitosis. By studying this peptide, you can gain insights into replisome integrity and DNA replication mechanisms, making it an invaluable tool for researchers in genetics, molecular biology, and cancer studies.

Key Features

• Peptide sequence: Histone H3 (44-63) with Lys56 acetylation
• Critical role in DNA damage repair and chromatin stability
• Facilitates understanding of cellular replication processes
• Useful in studying mitochondrial functions and associated mutations
• Ideal for various research applications in molecular biology

Specifications

Product	Details
Catalog Number	AnaSpec-10142
Weight	1 mg
Purity	≥95% by HPLC
Form	Lyophilized powder

FAQ

What is [Lys(Ac)56]-Histone H3 used for?

This peptide is primarily used for research in gene regulation, histone modifications, and understanding cellular mechanisms during cell division and DNA repair processes.

How should I store this peptide?

For optimal stability, store the peptide at -20°C, and avoid repeated freeze-thaw cycles. It is best to keep it in a desiccated environment.

Can I use this peptide in vivo?

This peptide is typically used in vitro for laboratory experiments to study its biochemical properties and interactions, rather than in live organisms.

Enhance your research with [Lys(Ac)56]-Histone H3 (44-63) today. This vital peptide can be purchased from our catalog of peptides, and while you’re exploring, don’t miss our other offerings like PKG Substrate and Autocamtide-2. Each peptide is designed to support your breakthrough research.

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