[Gln22]-beta-Amyloid (1-42), Dutch mutation – 0.5 mg

Overview

The [Gln22]-beta-Amyloid (1-42), Dutch mutation, is a specific peptide product that has gained attention in neurological research. This peptide represents a naturally occurring mutant of the wild type beta-Amyloid 1-42, known for its implications in familial cerebrovascular amyloidosis. The E22Q variant, often referred to as HCHWA-D, results from a single point mutation, substituting Glutamic acid with Glutamine at position 22. This change can significantly influence the peptide’s behavior in biological systems, making it a valuable tool for researchers.

Key Features

• Authentic Dutch E22Q beta-Amyloid peptide
• Critical for studying familial cerebrovascular amyloidosis
• Complementary to other peptides and assays available
• Stable in collapsed coil conformations
• Well-studied fibrils exhibit increased toxicity in certain models

Specifications

FAQ

What applications can the [Gln22]-beta-Amyloid peptide be used for?

This peptide is primarily used in research focused on Alzheimer’s disease and related conditions. It helps to understand the mechanisms of amyloid plaque formation and associated neurodegenerative processes.

How does the Dutch mutation affect the peptide’s properties?

The E22Q mutation alters the peptide’s interaction with proteins and cell membranes, increasing its tendency to form fibrils that are more toxic compared to the wild type. This makes it essential for understanding pathophysiological mechanisms.

Is the [Gln22]-beta-Amyloid peptide readily available?

Yes, you can easily purchase our [Gln22]-beta-Amyloid peptide online. It’s perfect for laboratories that require high-quality reagents for their research.

Enhance your research with the [Gln22]-beta-Amyloid (1-42), Dutch mutation. Purchase it today and explore its unique properties and applications.

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