[Gly22]-beta-Amyloid (1-42), Arctic Mutation – 0.5 mg

Name: [Gly22]-beta-Amyloid (1-42), Arctic Mutation | AnaSpec
SKU: AS-61967-05
Price: 497.00 USD
Availability: InStock

$497.00

[Gly22]-beta-Amyloid (1-42), Arctic Mutation, toxic soluble beta-amyloid assembly (TA-beta) formed more rapidly from 'Arctic' Aß than from wild-type .

SKU: AS-61967-05 Category: Peptides Tags: Alzheimer's research, Beta-Amyloid, peptides

Description
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Overview

The [Gly22]-beta-Amyloid (1-42), Arctic Mutation is a potent peptide that plays a crucial role in neurodegenerative research. This variant of beta-amyloid is characterized by a glycine substitution at position 22, which significantly enhances its aggregation properties, resulting in the formation of toxic soluble beta-amyloid assemblies (TA-beta) more rapidly than its wild-type counterpart. This peptide fragment is essential for studying Alzheimer’s disease mechanisms and evaluating potential therapeutic interventions.

Key Features

Mutant form of beta-amyloid (1-40) with glycine substitution at position 22
Rapid formation of toxic soluble assemblies in the presence of GM1 ganglioside
Essential for Alzheimer’s disease research and therapeutic development
Available in a convenient 0.5 mg package
High purity and quality for reliable experimental results

Specifications

Product	Concentration	Weight
[Gly22]-beta-Amyloid (1-42), Arctic Mutation	High purity	0.5 mg

FAQ

What is the significance of the Arctic mutation in beta-amyloid?

The Arctic mutation in beta-amyloid is known to enhance the peptide’s propensity to form aggregates. This leads to the quicker development of toxic soluble assemblies, which are critical for understanding Alzheimer’s disease progression.

How is this peptide used in research?

Researchers utilize [Gly22]-beta-Amyloid (1-42) to study the mechanisms of amyloid pathology in Alzheimer’s disease, allowing for the evaluation of new treatments targeting beta-amyloid aggregation.

Is the peptide suitable for therapeutic applications?

While this peptide is primarily for research purposes, insights gained from studies using [Gly22]-beta-Amyloid can inform the development of potential therapeutic strategies for Alzheimer’s and related disorders.

Explore our range of peptides to find more products suited to your research needs, including options like the Autocamtide-2 and CREBtide. With high-quality and reliable reagents, you can confidently advance your study on neurological and physiological indicators.