Overview
Insulin B (15-23) is a crucial peptide fragment derived from the insulin beta chain, specifically composed of amino acids 15 to 23. This peptide, often referred to as INS, is integral to diabetes research, particularly when examining the immune response of T cells associated with islet recognition. Researchers utilize this peptide in various assays, analyzing the production of important cytokines such as IFN-beta and IL-17 by both CD4 and CD8 T cells that contribute to diabetes pathology. Insulin B (15-23) plays a vital role in staining INS-reactive CTL clones, but it does not stain splenic CD8+ T cells from NOD or 8.3-TCR-transgenic NOD mice.
Key Features
- Specific fragment of the insulin beta chain.
- Essential for studying diabetes-related immune responses.
- Used to assay cytokine production, including IFN-beta and IL-17.
- Compatible with various immunological assays.
- Backed by thorough research and testing.
Specifications
| Item | Details |
|---|---|
| Product Name | Insulin B (15-23) |
| Quantity | 1 mg |
| Category | Peptides |
FAQ
What is Insulin B (15-23) used for?
This peptide is primarily used in diabetes studies to analyze the production of immune cytokines like IFN-beta and IL-17 by T cells.
How does Insulin B (15-23) interact with immune cells?
It specifically stains INS-reactive CTL clones, allowing researchers to examine the immune response in diabetes effectively.
Can I find other peptides for research at AnaSpec?
Certainly! You can explore a variety of other peptides in our catalog, including options like PKG Substrate (RKRSRAE) and Autocamtide-2 (KKALRRQETVDAL).
To support your research needs, buy Insulin B (15-23) today, and discover the impact this peptide can have in advancing your understanding of diabetes. Whether you’re conducting assays or exploring immune responses, this peptide fragment is a reliable choice for your laboratory investigations.
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