Overview
Fluorescein-Trp25-Exendin-4 (FLEX) is a specialized peptide designed for researchers needing reliable detection of human GLP-1 receptors. This unique conjugate combines Exendin-4 with fluorescein at the Tryptophan residue, providing a powerful tool in the study of GLP-1 receptor interactions. With FLEX, you get a peptide that retains full biological potency, ensuring your research remains relevant and impactful.
Key Features
- Equipotent to GLP-1(7-36)-amide and exendin-4.
- Specific and saturable binding to human GLP-1 receptors.
- Fluorescence anisotropy increases upon binding, facilitating detection.
- Kd value of 2.0 +/- 0.4 nM ensures high affinity.
- Ideal for cAMP stimulation assays in CHO cells.
Specifications
| Product Name | Fluorescein-Trp25-Exendin-4 (FLEX) |
| Quantity | 0.5 mg |
| Target | Human GLP-1 receptor |
| Binding Affinity | Kd = 2.0 +/- 0.4 nM |
FAQ
What applications is FLEX suited for?
FLEX is ideal for binding studies, receptor assays, and any research requiring detection of GLP-1 receptors in cellular models.
How do I store FLEX?
For optimal stability, store FLEX at -20°C and avoid repeated freeze-thaw cycles.
Can I use FLEX in vivo?
While FLEX is primarily designed for in vitro studies, its potency makes it a valuable tool in understanding GLP-1 receptor dynamics.
Boost your research efficacy with FLEX, a peptide that meets your labeling and detection needs. For related products, explore the quality of our PKG Substrate or consider our Autocamtide-2 for additional assays. Don’t forget to browse our extensive collection of peptides for more innovative solutions.




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