[Lys(Ac)5]-Histone H4 (1-21)-GGK(Biotin) – 1 mg

Name: [Lys(Ac)5]-Histone H4 (1-21)-GGK(Biotin) | AnaSpec
SKU: AS-64844-1
Price: 364.00 USD
Availability: InStock

$364.00

[Lys(Ac)5]-Histone H4 (1-21)-GGK(Biotin). Acetylation causes structural changes: amplify binding transcription factors to recognition sites in nucleosome.

SKU: AS-64844-1 Category: Peptides Tags: biotin, histone, peptides

Description
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Overview

Introducing our [Lys(Ac)5]-Histone H4 (1-21)-GGK(Biotin), a specialized peptide designed to facilitate advanced research in the field of epigenetics. This peptide includes the first 21 amino acids of histone H4, acetylated at Lys-5 and at the N-terminus. The incorporation of a biotinylated lysine at the C-terminus allows for easy detection and isolation, making it an ideal choice for studies involving protein interactions and transcription factor binding.

Key Features

Acetylated at Lys-5 and the N-terminus for enhanced interaction capabilities.
Biotinylated C-terminal lysine for straightforward detection using streptavidin and biotin techniques.
Facilitates the study of transcription factors binding to nucleosomes.
Available in 1 mg for concentrated applications.
Compatible with various assay kits available at AnaSpec for comprehensive research.

Specifications

Property	Details
Catalog Number	[Lys(Ac)5]-Histone H4 (1-21)-GGK(Biotin)
Quantity	1 mg
Category	Peptides

FAQ

What is the significance of acetylation in this peptide?

Acetylation at Lys-5 induces structural changes in histone H4, which are crucial for promoting the binding of transcription factors to their recognition sites within the nucleosome. This process is vital for understanding gene expression regulation.

How can I detect this peptide after use?

The biotinylated lysine allows for easy detection using streptavidin-based assays or other biotin-binding methods. You can combine it with our PKG Substrate for advanced applications.

Is this peptide suitable for in vivo studies?

This peptide is primarily designed for in vitro studies, particularly for exploring transcription factor interactions and epigenetic research. For further applications, consider our range of peptides available here.

By choosing [Lys(Ac)5]-Histone H4 (1-21)-GGK(Biotin), you’re investing in a high-quality peptide that’s essential for your research needs. Don’t miss out on enhancing your studies in gene expression and protein interactions. Order now and experience the benefits of our specialized peptide offerings!