Fibronectin-Laminin a1 Fusion Peptide, FN-A208 – 1 mg

Overview

The Fibronectin-Laminin a1 Fusion Peptide, FN-A208, is an innovative product designed for researchers exploring tissue regeneration and cell attachment. This unique peptide combines the A208 sequence derived from murine laminin a1 with the active site of fibronectin (GRGDS), separated by a glycine spacer. FN-A208 forms amyloid-like fibrils which are integral in promoting the formation of actin stress fibers, essential for fibroblast cell attachment.

Key Features

• Fusion of murine laminin a1 and fibronectin active site
• Promotes fibroblast cell attachment
• Forms amyloid-like fibrils
• Encourages actin stress fiber formation
• Interacts with IKVAV receptors and integrins
• Activity can be disrupted by EDTA

Specifications

FAQ

What is the primary use of FN-A208?

FN-A208 is primarily used for promoting fibroblast cell attachment in tissue engineering applications. Its unique structure enhances cell adhesion and can support regenerative medicine research.

How does FN-A208 interact with cells?

This peptide interacts with IKVAV receptors and integrins, crucial for cell attachment and migration. Such interactions can significantly facilitate the study of cell behavior in various biological contexts.

Is it sensitive to any conditions?

Yes, the activity of FN-A208 can be disrupted in the presence of EDTA, which chelates divalent cations essential for its functionality.

By incorporating FN-A208 into your research, you can advance your understanding of cellular interactions and enhance your projects in tissue regeneration. Explore more about our peptides and find the right tools to support your work today.

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