[Cit3]-Histone H4 (1-23)-GGK(Biotin) – 1 mg

Overview

The [Cit3]-Histone H4 (1-23)-GGK(Biotin) peptide is a specialized research tool designed for studying histone modifications and their effects on gene regulation. This peptide features a unique deimination at Arg3 and includes a C-terminal GGK linker with biotinylation on the side chain of lysine. Biotinylation allows for straightforward purification and detection, making it an ideal choice for various experimental applications involving protein interactions and post-translational modifications.

Key Features

• High purity peptide, >95%, ensures reliable results in your experiments.
• Biotinylation enhances the detection and isolation of the peptide.
• Custom designed for studies on histone modifications.
• Facilitates investigation into gene regulation processes.

Specifications

FAQ

What is the significance of deimination at Arg3?

Deimination at Arg3 is a post-translational modification that can affect the function of histones and thereby influence gene expression. Specifically, it has been shown to inhibit arginine methylation, which plays a role in gene activation and repression.

How is the biotinylation beneficial for my research?

Biotinylation allows for easy labeling, purification, and detection using streptavidin-based systems. This property is essential for many biochemical assays, enabling you to track protein interactions and modifications effectively.

Can I use this peptide in vivo?

While this peptide is primarily designed for in vitro studies, its application can be extended to in vivo settings depending on your research focus and the biological systems you are investigating.

Consider exploring our other peptides tailored for specific research needs, such as the Autocamtide-2 and CREBtideto enhance your studies on protein interactions and modifications.

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