Overview
The HIV-1 protease, recombinant, is a crucial enzyme in understanding and combating the HIV-1 virus. Weighing in at 10 to 12 kDa, this aspartic protease is essential for the post-translational cleavage of precursor polyproteins, including Gag, Gag-Pol, Pol, and Nef. Its activity is contingent upon forming a homodimer, highlighting its significance in the maturation process of HIV infectious particles. By targeting HIV-1 protease, researchers can develop effective anti-AIDS drugs that aim to inhibit viral replication and progression of the disease.
Key Features
- Recombinant HIV-1 protease derived from wild type (NCBI accession: NC_001802).
- Consists of a 99 amino acid sequence, ensuring accurate representation of the native enzyme.
- Essential for the processing and maturation of HIV infectious particles.
- A valuable tool for researchers studying viral replication and anti-HIV drug development.
- Available as a 5 µg quantity, perfect for various experimental needs.
Specifications
| Product Name | HIV-1 protease, recombinant |
| Quantity | 5 µg |
| Molecular Weight | 10-12 kDa |
| Amino Acids | 99 |
FAQ
What is the purpose of HIV-1 protease in the virus?
HIV-1 protease plays a critical role in the cleavage of precursor polyproteins, which is necessary for the maturation of infectious HIV particles.
How can I use recombinant HIV-1 protease in my research?
You can use recombinant HIV-1 protease to study the mechanisms of HIV replication and to screen potential inhibitors for drug development.
What are the storage conditions for the HIV-1 protease?
The recombinant HIV-1 protease should be stored at -20°C for long-term preservation. Ensure to aliquot to avoid repeated freeze-thaw cycles.
If you’re looking to make significant strides in HIV research, consider adding our recombinant HIV-1 protease to your lab’s toolkit. This product is part of our extensive catalog of recombinant proteins, including recombinant mouse MOG (1-125) and recombinant human MOG (1-125)which further facilitate advancements in proteomic studies. Discover the potential of our EndoClear™ Plus human recombinant a-Synuclein protein as well, and invest in quality research tools that reflect your commitment to scientific progress.
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