Overview
The MMP-9 (Catalytic Domain), human recombinant, is a vital tool for researchers studying matrix metalloproteinases (MMPs), a family of enzymes known for their ability to break down extracellular matrix components. This 92-kDa gelatinase plays a significant role in various physiological processes and is implicated in numerous diseases, including cancer, angiogenesis, alopecia, and metastasis. MMP-9 is secreted as a zymogen and possesses a catalytic domain, gelatin-binding domain, and other essential structural elements that facilitate its biological functions.
Key Features
- Human recombinant MMP-9 for consistent performance
- Ideal for research in cancer and cardiovascular studies
- Supports assays requiring gelatinase activity
- High purity level for reliable results
- Available in convenient sizes for varied research needs
Specifications
| Property | Details |
|---|---|
| Catalog Number | MMP-9-HR |
| Source | Human recombinant |
| Molecular Weight | 92 kDa |
| Form | Lyophilized powder |
| Storage Conditions | -20°C, avoid freeze-thaw cycles |
FAQ
What applications can MMP-9 (Catalytic Domain) be used for?
MMP-9 is widely used in research focusing on cancer metastasis, tissue remodeling, and inflammation. Its gelatinase activity makes it particularly useful in studies involving the extracellular matrix.
How should I store the MMP-9 protein?
It is recommended to store the MMP-9 at -20°C and to avoid repeated freeze-thaw cycles to maintain its activity and stability.
Can MMP-9 be used in cell culture experiments?
Yes, MMP-9 can be utilized in various in vitro experiments, including cell culture systems, to study its effects on cell behavior related to invasion and migration.
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