Amylin (22-27) [NMeG24, NMeI26], human (IAPP) – 1 mg

Overview

Our Amylin (22-27) [NMeG24, NMeI26], human (IAPP) is a highly specialized peptide designed for advanced research applications. This modified fragment of the human islet amyloid polypeptide (hIAPP) plays a critical role in understanding amyloid diseases. The N-methylation at specific sites G24 and I26 transforms this peptide from being amyloidogenic and cytotoxic into a non-amyloidogenic and non-cytotoxic form. You can rely on this peptide for studies focusing on the inhibition of fibrillogenesis and binding affinities with full-length hIAPP.

Key Features

• Modification of human islet amyloid polypeptide (hIAPP) for specific research applications.
• N-methylation at G24 and I26 enhances stability and reduces cytotoxicity.
• High-affinity binding capabilities with full-length hIAPP.
• Excellent for research in amyloid diseases and related physiological studies.
• Available in a convenient 1 mg quantity.

Specifications

FAQ

What is the significance of N-methylation in this peptide?

N-methylation at G24 and I26 alters the peptide’s properties, making it non-amyloidogenic and non-cytotoxic, which is crucial for safer research in amyloid diseases.

How should I store the Amylin peptide?

Store the Amylin (22-27) peptide in a cool, dry place at -20°C for long-term stability. Avoid repeated freeze-thaw cycles to maintain its integrity.

Can this peptide be used for in vitro studies?

Yes, this peptide is ideal for in vitro studies focusing on peptide interactions and the mechanisms underlying amyloid fibrillogenesis.

Explore our complete range of peptides to find more options suited for your research needs, or consider our PKG Substrate for specialized applications.

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