Overview
The Angiotensin I Converting Enzyme 2 (ACE-2) substrate is a highly sensitive fluorescent substrate designed for research involving ACE-2 activity. This substrate provides a significant fluorescence increase upon cleavage, making it an essential tool for studying biochemical pathways and potential therapeutic targets. With a maximum absorbance and emission at 325 nm and 393 nm, respectively, this substrate enables researchers to accurately quantify ACE-2 activity in a variety of sample types.
Key Features
- Fluorescent substrate specifically designed for ACE-2
- 300-fold increase in fluorescence upon complete hydrolysis
- Ideal for detecting enzyme activity in real-time
- Optimal absorption and emission maxima at 325 nm and 393 nm
- Available in a convenient 1 mg size
Specifications
| Parameter | Details |
|---|---|
| Product Name | ACE-2 Substrate |
| Size | 1 mg |
| Max Absorption | 325 nm |
| Max Emission | 393 nm |
FAQ
What is the mechanism of fluorescence increase?
The fluorescence of the ACE-2 substrate significantly increases (by 300 times) upon enzyme cleavage, allowing for effective monitoring of ACE-2 activity.
How should I store the substrate?
It’s best to store the ACE-2 substrate at -20°C, avoiding repeated freeze-thaw cycles to preserve its activity and integrity.
Can this substrate be used in vivo?
This substrate is primarily designed for in vitro assays. For in vivo studies, consider using a labeled version or related products such as our PKG substrate or Autocamtide-2.
Whether you’re conducting basic research or developing therapeutic strategies, the ACE-2 substrate is a valuable addition to your toolkit. Shop now to enhance your research capabilities and dive deep into enzyme activity analysis.
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