Beta-Amyloid (1-40) • HCl

Name: Beta-Amyloid (1-40) • HCl | AnaSpec
SKU: beta-amyloid-1-40-hcl-71c35e69-fe0c-4b55-b3a9-7010c377cd20
Availability: InStock

Price range: $251.00 through $401.00

All the HCl salt forms of Aß (1-40), Aß (25-35) and D-Ser26 Aß (25-35), take the ß-structure within a few hours in PBS. They form fibrils.

Size

Clear

SKU: beta-amyloid-1-40-hcl-71c35e69-fe0c-4b55-b3a9-7010c377cd20 Category: Peptides Tags: Alzheimer's research, neurobiology, peptides

Overview

Beta-Amyloid (1-40) • HCl is a crucial peptide widely studied for its role in neurological research, particularly in Alzheimer’s disease. This peptide, along with its counterparts Aß (25-35) and D-Ser26 Aß (25-35), is known to adopt a beta-structure in phosphate-buffered saline (PBS) within hours. The formation of fibrils is significant, as these aggregates can exert toxic effects on hippocampal cultured neurons and inhibit MTT reduction activity in non-neuronal cells such as HeLa without causing cytotoxicity.

For researchers examining the implications of amyloid beta in neurodegenerative conditions, understanding the behavior and characteristics of Beta-Amyloid (1-40) • HCl is essential. This knowledge can aid in the development of therapeutic interventions and provide deeper insights into the pathophysiological mechanisms of Alzheimer’s disease.

Key Features

Available in HCl salt form for convenient handling.
Forms fibrils rapidly, mimicking in vivo conditions.
Exhibits neurotoxic effects, making it critical for Alzheimer’s research.
Compatible with various assays for studying neurodegeneration.
Can be used alongside related compounds like PKG Substrate for extensive studies.

Specifications

Product Name	Beta-Amyloid (1-40) • HCl
Category	Peptides
Form	HCl Salt
Storage Conditions	-20°C

FAQ

What is the biological significance of Beta-Amyloid (1-40)?

Beta-Amyloid (1-40) is crucial in Alzheimer’s disease research. Its aggregation leads to neurodegeneration and cognitive decline, making it a target for therapeutic interventions.

How should I store this peptide?

Store Beta-Amyloid (1-40) • HCl at -20°C to maintain its stability and effectiveness for research applications.

Can this peptide be used in combination with other substrates?

Yes, this peptide can be effectively paired with other research substrates, such as Autocamtide-2to explore various pathways and mechanisms in neurobiology.

Explore our entire selection of peptides to find the best options for your research needs. Order Beta-Amyloid (1-40) • HCl today and enhance your studies in neurodegeneration!