Overview
Buforin 2, also known as Buforin II, is a 21 amino acid peptide derived from Buforin I, which is isolated from the Asian toad Bufo gargarizans. This peptide exhibits significant anti-microbial activity by penetrating bacterial membranes and inhibiting critical cellular functions. Its unique structure allows it to interact effectively with phospholipid bilayers, ensuring efficient translocation across these layers while maintaining a weak membrane permeabilization activity.
Key Features
- Antimicrobial properties: Effective against a range of bacterial strains.
- Unique structure: Comprises 21 amino acids with a proline hinge, enhancing its membrane interaction.
- Natural origin: Isolated from the Asian toad, ensuring a high degree of biological relevance.
- Low toxicity: Demonstrates low cytotoxic effects on human cells while being lethal to bacteria.
- Versatile applications: Ideal for research in microbiology and cellular biology.
Specifications
| Parameter | Details |
|---|---|
| Peptide length | 21 amino acids |
| Origin | Bufo gargarizans |
| Category | Peptides |
FAQ
What are the main applications of Buforin 2?
Buforin 2 is widely used in microbiological research due to its antimicrobial properties. It is particularly useful for studies on bacterial resistance and membrane interaction.
How should Buforin 2 be stored?
Store Buforin 2 at -20°C for long-term storage. It is recommended to avoid repeated freeze-thaw cycles to maintain the peptide’s integrity.
Can Buforin 2 be used in cell culture studies?
Yes, Buforin 2 can be utilized in cell culture studies to evaluate its antimicrobial effects on various bacterial strains while monitoring its impact on eukaryotic cells.
For researchers interested in expanding their studies, consider checking out related products like PKG Substrate or Autocamtide-2. Enhance your research capabilities with our selection of peptides and other assay kits available at AnaSpec.




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