![DiBAC4(3) [Bis-(1,3-dibutylbarbituric acid)trimethine oxonol] UltraPure Grade - 25 mg](https://anaspecstore.com/wp-content/uploads/2026/10/as-84700-img-en-as-84700-01.jpg)
DiBAC4(3) [Bis-(1,3-dibutylbarbituric acid)trimethine oxonol] UltraPure Grade – 25 mg
$285.00
Sensitive 488 nm-excitable membrane potential probe, ~1% fluorescence intensity change/mV; Sensitivity is temperature-dependent. When DiBAC4(3) enters into cells, it can bind to intracellular proteins or membrane and fluorescence.
Overview
DiBAC4(3), or Bis-(1,3-dibutylbarbituric acid)trimethine oxonol, is a highly sensitive membrane potential probe excitable at 488 nm. This UltraPure Grade product, available in a convenient 25 mg size, is designed for researchers focusing on cellular membrane potentials. The unique properties of DiBAC4(3) allow it to change fluorescence intensity in response to even slight shifts in membrane potential, making it an essential tool in various biological studies, including neuronal activity and physiological responses.
Key Features
- Excitation wavelength: 488 nm
- Approximate fluorescence intensity change of ~1% per mV
- Temperature-dependent sensitivity
- Binds to intracellular proteins or membranes
- Increases fluorescence upon cell depolarization
- Decreases fluorescence upon cell polarization
Specifications
| Specification | Detail |
|---|---|
| Product Name | DiBAC4(3) |
| Grade | UltraPure |
| Quantity | 25 mg |
| Excitation Peak | 488 nm |
FAQ
How does DiBAC4(3) function as a membrane potential probe?
DiBAC4(3) functions by entering cells and binding to intracellular proteins or membranes. The probe’s fluorescence increases with cell depolarization due to additional dye influx, while polarization results in reduced fluorescence.
Is DiBAC4(3) sensitive to temperature changes?
Yes, the sensitivity of DiBAC4(3) is temperature-dependent, which means that optimal results may vary with changes in ambient conditions. Always ensure consistent temperature during experiments.
Can DiBAC4(3) be used in live-cell imaging?
DiBAC4(3) is ideal for live-cell imaging as it effectively indicates changes in membrane potential in real-time, helping researchers monitor cellular activities dynamically.
Incorporating our Calcein, AM UltraPure Grade into your studies can complement the use of DiBAC4(3) by providing additional insights into cell viability. Explore more products in our Green (500 -550 nm) category for a wide range of research applications.
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