Histone H3 (69-89)-NH2 – 1 mg

Overview

Histone H3 (69-89)-NH2 is a specialized peptide used primarily for assessing the specificity of anti-H3K79me antibodies. This peptide sequence plays a crucial role in epigenetic research, particularly in studying histone modifications related to gene expression and chromatin dynamics. The methylation of Histone H3 lysine 79 (H3K79) is often connected to transcriptional activation, with the DOT/DOT1L enzyme catalyzing this process. Interestingly, aberrant methylation patterns of H3K79 have been associated with various forms of leukemia, highlighting its significance in cancer research.

Key Features

• Form: Acetylated peptide, ideal for immunological assays.
• Purity: High purity to ensure accurate results in experiments.
• Size: 1 mg, convenient for various lab needs.
• Use: Specifically designed for studying H3K79 methylation.
• Applications: Ideal for applications in proteomics and molecular biology.

Specifications

FAQ

What is the role of Histone H3 (69-89)-NH2 in research?

This peptide is primarily used to evaluate the specificity of antibodies targeting H3K79me methylation, which is critical for understanding epigenetic regulation in gene expression.

How should I store Histone H3 (69-89)-NH2?

To maintain its integrity, store this peptide at -20°C in a dry, cold environment, and avoid repeated freeze-thaw cycles.

Can I use Histone H3 (69-89)-NH2 for enzyme assays?

Yes, this peptide is designed for various assays, including those related to histone modification and enzyme activity studies.

To enhance your research capabilities, consider exploring our other peptides available for various applications.

If you are working on specific assays, don’t miss out on our PKG Substrate or the Autocamtide-2 for efficient experimentation.

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