[Lys(Me3)27]-Histone H3 (23-34)-GGK(Biotin) – 1 mg

Overview

The [Lys(Me3)27]-Histone H3 (23-34)-GGK(Biotin) peptide is an essential tool for researchers focused on epigenetic modifications. This histone H3 peptide is specifically trimethylated at Lys27 and biotinylated on the C-terminus via a GGK linker, making it an excellent choice for various assays. Its unique structure allows for precise interaction studies with Polycomb proteins and has implications in cancer research, particularly concerning methylated CpG island genes.

Key Features

• Trimethylated at Lys27 to enhance biological relevance.
• Biotinylated for easy detection and labeling in assays.
• High purity level (>95%) ensures reliable experimental outcomes.
• Supplied in a lyophilized powder form, ready for reconstitution.
• Effective for studying chromatin associations and gene regulation.

Specifications

FAQ

What is the significance of Lysine 27 trimethylation?

Lysine 27 trimethylation on histone H3 is a critical modification that influences gene expression by promoting the association of Polycomb group proteins with chromatin, ultimately leading to gene silencing.

How can I use this peptide in my experiments?

This biotinylated peptide can be utilized in various applications, including pull-down assays, western blotting, and chromatin immunoprecipitation (ChIP) assays, to study protein-DNA interactions and epigenetic regulation.

What is the best way to store this peptide?

For optimal stability, store the lyophilized peptide at -20°C. After reconstitution, store it at -80°C and avoid repeated freeze-thaw cycles to maintain its integrity.

Enhance your research with the [Lys(Me3)27]-Histone H3 (23-34)-GGK(Biotin) peptide, designed for studies in neuroscience and cancer biology. This high-purity peptide can seamlessly fit into your existing analysis workflow. Don’t miss out, shop now and order this peptide to further your research.

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