[Lys(Ac) 5/8/12/16]-Histone H4 (1-25)-GSGSK(Biotin) – 1 mg

Overview

Discover the potential of our [Lys(Ac) 5/8/12/16]-Histone H4 (1-25)-GSGSK(Biotin)a premium peptide specifically designed for researchers and scientists seeking to explore the intricate field of histone modification. This peptide consists of histone H4 residues 1-25, featuring acetylation at Lys5, Lys8, Lys12, and Lys16. The sequence is capped with a C-terminal GSGS linker, alongside a biotinylated lysine, facilitating easy detection and assay applications. With critical functions in transcriptional activation, DNA replication, and cell division, understanding the role of these acetylated residues can be essential for your research projects.

Key Features

• Biotinylated for straightforward labeling and detection
• Contains crucial acetylated lysines, enhancing binding with transcription factors
• C-terminal GSGS linker allows for flexible attachment in assays
• Essential for studying gene regulation and histone modification dynamics

Specifications

FAQ

What is the significance of acetylation at Lys5, Lys8, Lys12, and Lys16?

Acetylation at these lysine residues is vital for transcriptional activation and influences the interaction of transcription factors with DNA, thus playing key roles in gene expression.

How is the biotinylated lysine beneficial in my experiments?

The biotinylated lysine allows for easy attachment to streptavidin or avidin-coated surfaces, enabling effective detection and purification methods in various assays.

Can this peptide be used in cell culture studies?

Yes, this peptide can be utilized in cell culture studies to investigate the effects of histone acetylation on gene expression and cellular functions.

For additional resources, check out our PKG Substrate or explore more options in our Peptides category. This peptide is a vital addition to your toolkit for studying the effects of histone modifications.

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